The 15th Annual Real World Evidence stream at SCOPE Summit highlights the growing importance of data generated during routine healthcare, which is transforming both clinical and observational research. Patient electronic records, registries, pharmacy data, social media, and wearable sensors are increasingly used in registration studies. As the line between clinical trials and real-world data (RWD) research continues to blur, and RWD's role in clinical trials expands, innovative data technologies and strategic collaborations between pharmaceutical companies and data-holding organizations are becoming essential. AI plays a critical role in harnessing RWD, driving deeper insights and more efficient processes. This program is designed to connect stakeholders across the RWD research spectrum, including community and academic health centers, clinical trial sites, biopharma companies, and patient groups, facilitating the exchange of knowledge and experience.