Upcoming Global Web Symposia
May 15, 2012
11:30 – 1:00 pm EDT
Symposium Course Description:Eagle Genomics will lead a discussion about some real-world NGS use-cases and how the challenges were overcome. The case studies are from the fields of microbiology (Unilever) and animal health (the Roslin Institute) yet the techniques described are equally applicable to biomedical research. The short course will conclude with an analysis of a recent document from the Pistoia Alliance (www.pistoiaalliance.org) describing their view of the needs of big pharma in setting up pre-competitive collaborative online bioinformatics research environments that are specifically designed to cope with NGS.
Who Should Attend:
Richard Holland is a former lead developer on the open-source BioJava project and is a founder member of the Open Bioinformatics Foundation. Prior to co-founding Eagle in 2008, Richard worked on the BioMart team at the European Bioinformatics Institute, and before that at both AgResearch (New Zealand) and the A*STAR Genome Institute of Singapore on sequencing database projects. Richard holds a BSc in Computer Science from the University of Otago (New Zealand) and is a member of the British Computer Society (BCS).
Mick Watson, currently Director of the ARK-Genomics centre for comparative and functional genomics, is an established bioinformatician, with 14 years experience in industry and academia. He was involved in the implementation and management of pipelines for functional genomics at GlaxoWellcome, SNP discovery at Incyte Genomics and Target Discovery at Paradigm Therapeutics, before joining the Institute for Animal Health as Head of Bioinformatics in 2002. His group’s research focuses on the use of computational and mathematical techniques to understand genome function with an emphasis on transcriptomic analysis in systems of relevance to animal health and food security. This focus has resulted in the development of several novel bioinformatics software applications, and the analysis and integration of a diverse array of data, including genome sequence, gene expression, next generation sequencing and proteomics data, with the aim of predicting the function of genetic elements. Publications include both primary bioinformatics research papers and collaborative research in a variety of technical and scientific journals. The outputs from his research have included novel algorithm development, as well as the application of bioinformatics techniques to analyse the bovine immune response, Salmonella genomics and the structure and function of microRNAs.
Pete Keeley Has worked in IT for 30 years with various software houses as a Database designer/consultant prior to joining Unilever Research.
Currently engaged in Unilever Research's eScience program identifying candidate technical platforms that will enable us to manage and visualise the ever-growing data sizes we are working with.
William Spooner is a seasoned operational bioinformatician with a track record of delivering tools for high-throughput genomics research. Having worked previously on Ensembl, BioMart, Gramene and WormBase at the European Bioinformatics Institute, the Wellcome Trust Sanger Institute and Cold Spring Harbor, his current focus is on making life easier for users of open source/data in commercial settings. His strategic thinking is driven by the huge opportunities for data analysis in the life sciences provided by the near simultaneous arrival of NGS and cloud computing.
Richard Holland, Chief Business Officer, Eagle Genomics Ltd, Experts in Genome Content Management
Mick Watson, Director, ARK Genomics, Roslin Institute, University of Edinburgh , UK
As an international centre of expertise in animal genomics and genetics, ARK-Genomics generates a diverse range of data from high-throughput technologies. This presentation will discuss the work of ARK-Genomics and the challenges faced when dealing with such diverse data. I will then go on to discuss specific challenges in managing microRNA-Seq data, and our project with Eagle genomics which attempts to address these.
Pete Keeley, IT Lead - eScience R&D IT, Global Solutions, Unilever Research, UK
David Taylor, Science Area Leader Microbiology, Unilever Research, UK
This presentation will talk about what Unilever is using NGS for, how their resources were beginning to struggle with coping with the data, use-case of how they used the cloud to address this.
William H Spooner, Founder and CTO, Eagle Genomics, UK
In 2011 the Pistoia Alliance published their vision for a platform to users where they can solve scientific problems based on DNA/RNA sequence information, tailored to the needs of the pharmaceutical industry. This presentation will talk about their requirements in the context of existing tools, and address the challenges of architecting and securing an enterprise level service for sequence analysis.
12:50 Interactive Q&A
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